Anti Viral Therapy and Its Future
Naama Elefant, a researcher at the Hebrew University analyzed the function of microRNAs that led to the discovery.
Viruses are responsible for some of the most debilitating diseases known to mankind, such as avian influenza, AIDS, Ebola, SARS, common cold, chickenpox, influenza, diarrhea, etc. While some of these diseases are taken care of quite well by the immune system viz. common cold, diarrhea, against others such as the HIV, the human body is quite helpless. Although anti-viral drugs such as the HIV drugs do help in slowing down the infection but the current pharmaceutical drugs are nowhere near to completely treat the infection.
The new research focuses on the microRNA genes, which are found in many organisms. Discovered in 1993, microRNA play a big role in a range of biological processes. Their significance in the present study pertains to their ability to inhibit the production of proteins, which are the building blocks of cell and must be produced at the right time and place. MicroRNA genes inhibit proteins by attaching themselves to the proteins. The protein that a microRNA attacks is considered as its target.
The outcome of the research has been the development of an algorithm called RepTAR, which can predict the next target of a microRNA. The RepTAR works by searching thousands of genes in a human through, structural, sequence and physical characteristics and upon identification matches them to hundreds of microRNAs.
Implications for Anti-viral therapy
This technique has helped in finding a group of microRNAs present in viruses. Further research highlighted that microRNAs did indeed inhibit the genes in the human immune system.
Consequently, the anti-viral pharmaceuticals in the future could aim at inhibiting viral microRNA to treat an infection.
Viruses such as HIV are perhaps the biggest scare and the drugs used against it aren't effective enough to save lives, if this discovery leads to a formulation that's effective enough, then it would perhaps be one of the finest discoveries in human history.
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Viruses are responsible for some of the most debilitating diseases known to mankind, such as avian influenza, AIDS, Ebola, SARS, common cold, chickenpox, influenza, diarrhea, etc. While some of these diseases are taken care of quite well by the immune system viz. common cold, diarrhea, against others such as the HIV, the human body is quite helpless. Although anti-viral drugs such as the HIV drugs do help in slowing down the infection but the current pharmaceutical drugs are nowhere near to completely treat the infection.
The new research focuses on the microRNA genes, which are found in many organisms. Discovered in 1993, microRNA play a big role in a range of biological processes. Their significance in the present study pertains to their ability to inhibit the production of proteins, which are the building blocks of cell and must be produced at the right time and place. MicroRNA genes inhibit proteins by attaching themselves to the proteins. The protein that a microRNA attacks is considered as its target.
The outcome of the research has been the development of an algorithm called RepTAR, which can predict the next target of a microRNA. The RepTAR works by searching thousands of genes in a human through, structural, sequence and physical characteristics and upon identification matches them to hundreds of microRNAs.
Implications for Anti-viral therapy
This technique has helped in finding a group of microRNAs present in viruses. Further research highlighted that microRNAs did indeed inhibit the genes in the human immune system.
Consequently, the anti-viral pharmaceuticals in the future could aim at inhibiting viral microRNA to treat an infection.
Viruses such as HIV are perhaps the biggest scare and the drugs used against it aren't effective enough to save lives, if this discovery leads to a formulation that's effective enough, then it would perhaps be one of the finest discoveries in human history.
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Firefox is recommended for good speed of the web surfing
Update your PC or Laptop with Latest Free Software for safe browsing
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Banana Allergy: Banana is an edible fruit that can also result in allergic reactions after consuming it. The symptoms of this type of allergy include itching, swollen lips, hives, stomach infections, asthma and even a slight drop in blood pressure. Those who get instant reactions just after consuming banana or banana based products should consult a doctor and stop consuming it until a proper diagnose is done. To identify this allergy, banana skin test along with a blood test can be undertaken. Once it is detected patients should avoid the intake of both fresh banana and banana based products. A banana free diet should be followed and anti-allergy
Footwear Allergy: is basically a type of inflammation that occurs when skin of the foot comes in contact with a particular substance such as rubber, chemicals used in tanning leather, adhesives and dyes. It results in red and swollen skin that can blister. To diagnose allergies caused by footwear, a patch testing is performed. In this type of test, small amounts of potential allergens are directly applied onto the skin with tape strips, which are removed after a span of two days. People with footwear allergy can be treated medically.
Egg Allergy: is one of the types of food allergy. It usually occurs within minutes to hours after consuming eggs in any form. The symptoms of egg allergy are wheezing, headache, nausea, stomachache, and itchy hives. A worst form of egg allergy could lead to anaphylaxis, which may result into swelling of mouth, throat and lungs, and even decrease in blood pressure. Those who are extremely allergic to eggs may get anaphylactic reaction even by inhaling egg fumes or getting egg on the skin. Egg allergy can be diagnosed by performing a skin test. This type of allergy can be treated medically by using antihistamines or epinephrine. If you are highly sensitive to egg, then you should avoid both fresh egg or egg based products. You can even try egg free products and make sure you scrub the utensils carefully that contains eggs while cooking at home.